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HelpTest Code SSCP Systemic Sclerosis Criteria Panel, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.7 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Secondary ID
622520Useful For
Evaluating patients with antinuclear antibody-associated connective tissue disease, specifically systemic sclerosis
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| NAIFA | Antinuclear Ab, HEp-2 Substrate, S | Yes | Yes |
| SCL70 | Scl 70 Ab, IgG, S | Yes | Yes |
| RNAP | RNA Polymerase III Ab, IgG, S | Yes | Yes |
Method Name
NAIFA: Indirect Immunofluorescence
SCL70: Multiplex Flow Immunoassay
RNAP: Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Systemic Sclerosis Panel, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimens | Reject |
Reference Values
ANTINUCLEAR ANTIBODIES, HEp-2 SUBSTRATE, IgG
<1:80 (Negative)
Scl 70 ANTIBODIES, IgG
<1.0 U (negative)
≥ 1.0 U (Positive)
RNA POLYMERASE III ANTIBODIES, IgG
<20.0 U (Negative)
20.0-39.9 U (Weak positive)
40.0-80.0 U (Moderate positive)
>80.0 U (Strong positive)
Day(s) Performed
Tuesday, Thursday
Report Available
2 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86039
86235
83516
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SSCP | Systemic Sclerosis Panel, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SCL70 | Scl 70 Ab, IgG, S | 47322-3 |
| RNAP | RNA Polymerase III Ab, IgG, S | 79182-2 |
| ANAH | Antinuclear Ab, HEp-2 Substrate, S | 59069-5 |
| 1TANA | ANA Titer: | 33253-6 |
| 1PANA | ANA Pattern: | 49311-4 |
| 2TANA | ANA Titer 2: | 33253-6 |
| 2PANA | ANA Pattern 2: | 49311-4 |
| CYTQL | Cytoplasmic Pattern: | 55171-3 |
| LCOM | Lab Comment: | 77202-0 |